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The study also addressed safety concerns about the drug and identified the most common side effects.
Dizziness, dissociation, dysgeusia (change or distortion in sense of taste), vertigo, and nausea were the most common side effects of the drug. Most tended to occur shortly after dosing and cleared up within 90 minutes.
Nine patients stopped the trial after experiencing adverse events including headache, panic attack, and “feeling drunk.”
However, the consensus of the study was that overall the drug was safe and tolerable.
“Most experts and clinicians feel that the marketing of intranasal esketamine will be a boon for a subset of patients who suffer greatly and for whom other currently available treatments have been insufficiently effective,” Dr. Timothy B. Sullivan, chair of psychiatry and behavioral sciences at Staten Island University Hospital in Staten Island, NY, told Healthline.
Sullivan wasn’t involved in the research.
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